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To thoroughly review the uses of human chorionic gonadotropin (hCG) related to the process of reproduction and also assess new, non-traditional theories. Review of the international literature and research studies. hCG and its receptor, LH/CGR, are expressed in numerous sites of the reproductive tract, both in gonadal and extra-goanadal tissues, promoting oocyte maturation, fertilization, implantation and early embryo development. Moreover, hCG seems to have a potential role as an anti-rejection agent in solid organ transplantation. Future research needs to focus extensively on the functions of hCG and its receptor LH/CGR, in an effort to reveal known, as well as unknown clinical potentials.Keywords: hCG, LH/CGR, ovulation induction, oocyte maturation, endometrial synchrony, immunization

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An HCG pregnancy test checks human chorionic gonadotropin (HCG) levels in the blood or urine. HCG tests can detect elevated HGC levels to determine if a person is pregnant.HCG tests can also determine if a person’s body is producing the correct levels of certain pregnancy-related hormones. Typically, HCG levels increase steadily during the first trimester, peak, then decline in the second and third trimesters as the pregnancy progresses.Doctors may order several HCG blood tests over several days to monitor how a person’s HCG levels change. This HCG trend can help doctors determine how a pregnancy is developing.

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