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No. The HCG diet isn't safe, and it doesn't lead to long-term weight loss. HCG stands for human chorionic gonadotropin. It's a hormone made in the body during pregnancy. Lab-made HCG is added to some weight-loss products that are sold without a prescription. The U.S. Food and Drug Administration (FDA) warns against using these products. The HCG diet combines these weight-loss products with a very low-calorie eating plan.

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Photo showing a urine sample that has tested positive for human chorionic gonadotropin (hCG). This hormone is secreted by the placenta in pregnant women.Human chorionic gonadotrophin (hCG) is a hormone produced by the cells that surround the growing human embryo that go on to form the placenta (called trophoblasts). Human chorionic gonadotrophin can be detected in the urine from 7-9 days after fertilisation as the embryo attaches and implants in the womb; it forms the basis of most over-the-counter and hospital pregnancy tests (see photo).