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Aug . 16, 2023 17:04 Back to list

Semax cas 80714-61-0 at wholesale price whatsapp:+86-19031013676



Semax cas 80714-61-0 at wholesale price whatsapp:+86-19031013676

MEHFPGP is a neuroprotective peptide. MEHFPGP can be used in stroke research

MEHFPGP (25μM and 100μM, 48 h) reduced Abeta oligomers (100μM) levels [2]. MEHFPGP (100nM) increases the survival of cholinergic basal forebrain neurons [3]. MEHFPGP (100 nM) stimulated choline acetyltransferase activity in free basal forebrain tissue culture [3]. MEHFPGP (10μM, 24 h) stimulated the synthesis of brain-derived neurotrophic factor (BDNF) in astrocytes cultured from the basal forebrain of rats

MEHFPGP (Semax, 100μg/kg, i.p.) promotes the formation and function of the vascular system during ischemia (pMCAO) in rats [1]. MEHFPGP (50µg and 250µg, 100µL/kg, intranasal inhalation) increased the level of BDNF protein in the basal forebrain of rats [5]. Animal model: Ischemic (pMCAO) rat [1]. Dose: 100μg/kg Administration: Intraperitoneal injection (i.p.) 15 minutes, 1, 4, and 8 hours after permanent middle cerebral artery occlusion (pMCAO). Results: The immune response was enhanced (the transcription was upregulated). Animal model: rat [5] Dose: 50µg, 250µg, 100µL/kg Administration: Nasal inhalation Results: Increased levels of brain-derived neurotrophic factor (BDNF) protein in the basal forebrain of rats

Physical and chemical properties of Semax

Density 1.391g/cm3

Boiling point 1335.2ºC at 760 mmHg

Molecular formula C37H51N9O10S

Molecular weight 813.92000

Flash point 761.3ºC

Accurate mass 813.34800

PSA 325.58000

LogP 2.71460

Refractive index 1.617

Description of necessary first aid measures

1.1 suction

If inhaled, remove the patient to fresh air. If you stop breathing, give artificial respiration.

Skin contact

Rinse with soap and plenty of water.

Eye contact

Rinse your eyes with water as a precaution.

ingestion

Do not feed anything from the mouth to an unconscious person. Rinse your mouth with water.

1.2 Main symptoms and effects, acute and late effects

To the best of our knowledge, this chemical, physical and toxic property has not been fully studied

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