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Case reports and small studies indicate that anabolic steroids increase irritability and aggression,75 although findings may be confounded by personality traits that are overrepresented in steroid users (i.e., antisocial, borderline, and histrionic personality disorder)78 and use of other drugs.79 People who misuse anabolic steroids report more anger than nonusers,80 as well as more fights, verbal aggression, and violence toward their significant others,81 sometimes called "roid rage." One study suggests that the mood and behavioral effects seen during anabolic-androgenic steroid misuse may result from secondary hormonal changes.82

Anabolic steroids are synthetically produced variants of the naturally occurring male hormone testosterone that are abused in an attempt to promote muscle growth, enhance athletic or other physical performance, and improve physical appearance.

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