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Jun . 30, 2023 09:36 Back to list

DSIP CAS 62568-57-4



  • DSIP CAS 62568-57-4 WHATSAPP:+86-19031013676

  • Emiditide is a neuropeptide that has antioxidant and anti-anxiety effects

  • 1. In vivo study
  • Inrabbitinfusedwithδ-SleepInducingPeptide(DSIP),thespindleactivityisincreased,andheartandrespirationratearemoderatelydecreased.δ-SleepInducingPeptide(DSIP)mayactasaprogrammingmodulatoratsupra-operationallevelratherthanasatransmitteratoperatiChemicalbookonallevel.δ-SleepInducingPeptide(DSIP;40μg/kg,i.p.)increasescatalaseandsuperoxidedismutase(SOD)activitiesandmalonicdialdehyde(MDA)concentrationintheliverhomogenateofratssubjectedtoacutestress,buttheoppositeeffectsareobservedat120,and360μg/kg.
  • Properties of emidide Boiling point 1522.7±65.0°C(Predicted) Density 1.458±0.06g/cm3(Predicted) Storage conditions −20°C Shape Powder Acidity coefficient (Predicted) 3.18±0.10(Predicted) Water solubility Solution and Solubleinwaterat0.5 mg/mlInChIKeyZRZROXNBKJAOKB - GFVHOAGBSA - N
  • 2. solubility

    3. In Vitro:

    H 2 O.

     

    4. Peptide solubility and storage guidelines:

     

    1. Calculate the length of the peptide.

     

    2. Calculate the total charge of the entire peptide according to the following table:

     

    Content assignment value Acidic amino acids Asp (D), Glu (E) and C-terminal -COOH. -1 Basic amino acids Arg (R), Lys (K), His (H) and N-terminal -NH 2+1 neutral amino acids Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

    3. Recommended solutions:

     

    The total charge detail of the peptide is negative (<0) 1. First try to dissolve the peptide in water. 2. If the water fails, add NH 4 OH (<50μL). 3. If the peptide still does not dissolve, add DMSO (50-100μL) to dissolve the peptide. Positive (> 0) 1. First try to dissolve the peptide in water. 2. If water fails, try to dissolve the peptide in a solution of 10%-30% acetic acid. 3. If the peptide still does not dissolve, try to dissolve the peptide in a small amount of DMSO. 0 (= 0) 1. First try to dissolve the peptide in organic solvents (acetonitrile, methanol, etc.). 2. For very hydrophobic peptides, try to dissolve the peptide in a small amount of DMSO and then dilute the solution with water to the desired concentration.

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