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  • I-DSIP CAS 62568-57-4

Jun . 30, 2023 09:36 Buyela ohlwini

I-DSIP CAS 62568-57-4



  • I-DSIP CAS 62568-57-4 WHATSAPP:+86-19031013676

  • I-Emiditide iyi-neuropeptide ene-antioxidant ne-anti-anxiety effects

  • 1. Nge vivo funda
  • I-Inrabbitin ixutshwe ne-δ-SleepInducingPeptide(DSIP),umsebenzi womgogodla uyenyuka,nenhliziyo kanye nokuphefumula kunciphile ngokumaphakathi.δ-SleepInducingPeptide(DSIP)mayactasaprogrammingmodulatoratsupra-operationallevelratherthanasatransmitteratonatiPlevelUmdweboI-DSμincwadiUmdweboI-DSμumdwebo. ,ip)inyusa i-scatalaseandsuperoxidedismutase(SOD)imisebenzi kanye nemalonicdialdehyde(MDA)concentrationintheliverhomogenateofratssubject tocutestress,butthetheopposite effect igcinwa ku-120,and360μg/kg.
  • Izakhiwo ze-emidi Indawo yokubilisa 1522.7±65.0°C(Kubikezelwe) Ukuminyana 1.458±0.06g/cm3(Kubikezelwe) Izimo zesitoreji −20°C Umumo We-Powder Coefficient (Kubikezelwe) 3.18±0.10(Okubikezelwe) Ukuncibilika kwamanzi Isixazululo kanye ne-Solubleinwaterat0.5 mg/mlInChIKeyZRZROXNBKJAOKB - GFVHOAGBSA - N

  • 2. ukuncibilika

    3. In Vitro:

    H2 O.

     

    4. Iziqondiso zokuncibilika kwe-peptide kanye nesitoreji:

     

    1. Bala ubude be-peptide.

     

    2. Bala inani eliphelele le-peptide yonke ngokwethebula elilandelayo:

     

    Inani lesabelo sokuqukethwe I-Acidic amino acid Asp (D), Glu (E) kanye ne-C-terminal -COOH. -1 Basic amino acids Arg (R), Lys (K), His (H) kanye N-terminal -NH 2+1 neutral amino acids Gly (G), Ala (A), Leu (L), Ile (I) , Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), I-Tyr (Y), i-Trp (W), i-Pro (P), i-Asn (N), i-Gln (Q) 0

    3. Izixazululo ezinconyiwe:

     

    Ingqikithi yokushajwa kwemininingwane ye-peptide inegethivu (<0) 1. Okokuqala zama ukuncibilikisa i-peptide emanzini. 2. Uma amanzi ehluleka, engeza i-NH 4 OH (<50μL). 3. Uma i-peptide ingakancibiliki, engeza i-DMSO (50-100μL) ukuze uncibilikise i-peptide. Okuhle (> 0) 1. Okokuqala zama ukuncibilikisa i-peptide emanzini. 2. Uma amanzi ehluleka, zama ukuncibilikisa i-peptide ngesisombululo se-acetic acid engu-10% -30%. 3. Uma i-peptide ingakancibiliki, zama ukuncibilikisa i-peptide ngenani elincane le-DMSO. 0 (= 0) 1. Okokuqala zama ukuncibilikisa i-peptide kuzincibilikisi zemvelo (i-acetonitrile, i-methanol, njll.). 2. Ngama-peptide ane-hydrophobic kakhulu, zama ukuncibilikisa i-peptide ngenani elincane le-DMSO bese uhlanza isixazululo ngamanzi ekugxiliseni okufunayo.

Yabelana
Olandelayo:

Izindaba zakamuva
Asset 3

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