I-Semax cas 80714-61-0 ngentengo yokuthengisa

I-MEHFPGP iyi-peptide ye-neuroprotective. I-MEHFPGP ingasetshenziswa ocwaningweni lwe-stroke

I-MEHFPGP (25μM kanye ne-100μM, 48 h) yehlise amazinga e-Abeta oligomers (100μM) [2]. I-MEHFPGP (100nM) inyusa ukusinda kwe-cholinergic basal forebrain neurons [3]. I-MEHFPGP (i-100 nM) ikhuthaze umsebenzi we-choline acetyltransferase kusiko samahhala se-basal forebrain tissue culture [3]. I-MEHFPGP (10μM, 24 h) ikhuthaze ukuhlanganiswa kwe-brain-derived neurotrophic factor (BDNF) kuma-astrocyte akhuliswe kusukela ku-basal forebrain yamagundane.

I-MEHFPGP (i-Semax, i-100μg/kg, ip) ikhuthaza ukwakheka nokusebenza kwesistimu ye-vascular ngesikhathi se-ischemia (pMCAO) kumagundane [1]. I-MEHFPGP (i-50µg ne-250µg, i-100µL/kg, i-intranasal inhalation) inyuse izinga le-BDNF protein ku-basal forebrain yamagundane [5]. Imodeli yezilwane: I-Ischemic (pMCAO) rat [1]. Umthamo: 100μg/kg Ukuphatha: Umjovo we-Intraperitoneal (ip) imizuzu engu-15, i-1, 4, namahora angu-8 ngemva kokuvaleka komthambo we-cerebral ophakathi nendawo (pMCAO). Imiphumela: Ukusabela kwamasosha omzimba kuye kwathuthukiswa (okulotshiweyo kwalawulwa ngokomthetho). Imodeli yezilwane: igundane [5] Umthamo: 50µg, 250µg, 100µL/kg Ukuphatha: Ukuhogela amakhala Imiphumela: Amazinga anyusiwe we-brain-derived neurotrophic factor (BDNF) protein ku-basal forebrain yamagundane

Izakhiwo zomzimba namakhemikhali ze-Semax

Ukuminyana 1.391g/cm3

Iphoyinti lokubilisa 1335.2ºC ku-760 mmHg

Ifomula yemolekyuli C37H51N9O10S

Isisindo samangqamuzana 813.92000

Iphoyinti le-Flash 761.3ºC

Isisindo esinembile 813.34800

I-PSA 325.58000

Idatha ye-2.71460

Inkomba ye-Refractive 1.617

Incazelo yezinyathelo zosizo lokuqala ezidingekayo

1.1 ukuncela

Uma uhogeliwe, khipha isiguli emoyeni omusha. Uma uyeka ukuphefumula, nikeza ukuphefumula okwenziwa.

Ukuthintana kwesikhumba

Hlanza ngensipho namanzi amaningi.

Ukubheka ngamehlo

Hlanza amehlo akho ngamanzi njengesinyathelo sokuzivikela.

ukungeniswa

Ungadli lutho olusuka emlonyeni uye kumuntu oqulekile. Hlanza umlomo wakho ngamanzi.

1.2 Izimpawu nemiphumela esemqoka, imiphumela ebuhlungu nephuzile

Ngokwazi kwethu, le khemikhali, impahla ebonakalayo kanye nobuthi ayikafundwa ngokugcwele

I-Semax cas 80714-61-0 ngentengo yokuthengisa

I-MEHFPGP iyi-peptide ye-neuroprotective. I-MEHFPGP ingasetshenziswa ocwaningweni lwe-stroke

I-MEHFPGP (25μM kanye ne-100μM, 48 h) yehlise amazinga e-Abeta oligomers (100μM) [2]. I-MEHFPGP (100nM) inyusa ukusinda kwe-cholinergic basal forebrain neurons [3]. I-MEHFPGP (i-100 nM) ikhuthaze umsebenzi we-choline acetyltransferase kusiko samahhala se-basal forebrain tissue culture [3]. I-MEHFPGP (10μM, 24 h) ikhuthaze ukuhlanganiswa kwe-brain-derived neurotrophic factor (BDNF) kuma-astrocyte akhuliswe kusukela ku-basal forebrain yamagundane.

I-MEHFPGP (i-Semax, i-100μg/kg, ip) ikhuthaza ukwakheka nokusebenza kwesistimu ye-vascular ngesikhathi se-ischemia (pMCAO) kumagundane [1]. I-MEHFPGP (i-50µg ne-250µg, i-100µL/kg, i-intranasal inhalation) inyuse izinga le-BDNF protein ku-basal forebrain yamagundane [5]. Imodeli yezilwane: I-Ischemic (pMCAO) rat [1]. Umthamo: 100μg/kg Ukuphatha: Umjovo we-Intraperitoneal (ip) imizuzu engu-15, i-1, 4, namahora angu-8 ngemva kokuvaleka komthambo we-cerebral ophakathi nendawo (pMCAO). Imiphumela: Ukusabela kwamasosha omzimba kuye kwathuthukiswa (okulotshiweyo kwalawulwa ngokomthetho). Imodeli yezilwane: igundane [5] Umthamo: 50µg, 250µg, 100µL/kg Ukuphatha: Ukuhogela amakhala Imiphumela: Amazinga anyusiwe we-brain-derived neurotrophic factor (BDNF) protein ku-basal forebrain yamagundane

Izakhiwo zomzimba namakhemikhali ze-Semax

Ukuminyana 1.391g/cm3

Iphoyinti lokubilisa 1335.2ºC ku-760 mmHg

Ifomula yemolekyuli C37H51N9O10S

Isisindo samangqamuzana 813.92000

Iphoyinti le-Flash 761.3ºC

Isisindo esinembile 813.34800

I-PSA 325.58000

Idatha ye-2.71460

Inkomba ye-Refractive 1.617

Incazelo yezinyathelo zosizo lokuqala ezidingekayo

1.1 ukuncela

Uma uhogeliwe, khipha isiguli emoyeni omusha. Uma uyeka ukuphefumula, nikeza ukuphefumula okwenziwa.

Ukuthintana kwesikhumba

Hlanza ngensipho namanzi amaningi.

Ukubheka ngamehlo

Hlanza amehlo akho ngamanzi njengesinyathelo sokuzivikela.

ukungeniswa

Ungadli lutho olusuka emlonyeni uye kumuntu oqulekile. Hlanza umlomo wakho ngamanzi.

1.2 Izimpawu nemiphumela esemqoka, imiphumela ebuhlungu nephuzile

Ngokwazi kwethu, le khemikhali, impahla ebonakalayo kanye nobuthi ayikafundwa ngokugcwele