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Aug. 08, 2023 15:20 Hoʻi i ka papa inoa

ʻO Thymalin cas 63958-90-7 whatsapp:+86-19031013676



Thymalin cas 63958-90-7

He kūpono ia no nā maʻi maʻi maʻi mua a me ka lua, nā maʻi i hoʻokumu ʻia e ka immune dysfunction, adjuvant treatment of tumors, aplastic anemia, acute and chronic viral hepatitis, a hiki ke hoʻohana ʻia no ka lupus erythematosus, rheumatoid arthritis, allergic asthma, etc.

Serum thymic mea kumu kumu e paila ai 1658.9 + / - 65.0 ° C (Wanamua) 1.417 + 0.06 g/cm3 mānoanoa (Wanamua) kūlana waiho - 20 ° C solubility dChemicalbookeionizedwater: soluble acidity coefficient (pKa) 3.0 8±0.10(Wanamua) Lyophilizedpowder Kala keokeo

He mea koʻikoʻi ka Serum thymus factor e hāpai i ka ʻokoʻa lymphocyte a hoʻonui i kāna hana. Hiki iā ia ke hoʻoulu i ka hana cell immune, hoʻoponopono i ka hana immune a hoʻonui i ka palekana cellular non-specific. Hiki i nā huahana kemika ke hoʻoponopono i ka hana immune cell, me ka anti-aging, nā hopena antiviral. He paʻa paʻa i ka wela, ʻaʻole emi ka hana olaola ma 80 ℃, a nalowale ka hana olaola ma hope o ka hydrolyzed i loko o nā waikawa amino. Ua hoʻohana ʻia ka pipi thymus e like me ka mea maka, ka momona, ka fascia a me nā ʻiʻo non-thymus ʻē aʻe i wehe ʻia, i hoʻopaʻa ʻia i ka -20 ℃, holoi ʻia me ka wai distilled sterile, a hoʻopaʻa ʻia i loko o kahi mīkini ʻiʻo sterilized. Wahi a ka lakio nui o 1: 1, lawe ʻia ka thymus i ʻoki ʻia me ka wai anuanu no ka injection (Hoʻopuka ʻia ka wai Kina me ka haʻahaʻa haʻahaʻa a me ka hoʻoheheʻe anuanu), hiki ke hoʻoheheʻe ʻia ka peptide ikaika i ka wai a hoʻomaikaʻi i ka hua. Wahi a nā hōʻike haole, hiki ke unuhi ʻia me ka saline maʻamau) i hui ʻia, waiho ʻia i loko o ka 10000r / min kiʻekiʻe-wikiwiki masher, a mashed no 1min e hana i ka homogenize. Calf thymus [honua] → thymus ʻoki ʻia [ka wai anuanu no ka injection]→[10000r/min,1min] Thymus homogenate ʻāpana o ka thermal denaturation, centrifugation, filtration Ua hoʻomoʻi ʻia ka homogenate thymus ma lalo o 10 ℃, a laila maloʻo ma -2chemical book0 ℃ no 48h. Ma hope o ka hoʻoheheʻe ʻana, e hoʻoulu i ka ʻauʻau wai a me ka wela a hiki i 80 ℃, mālama no 5min, hoʻomaha wikiwiki, hoʻomoʻa i ka -20 ℃ no 2-3d. Ma hope o ka hoʻoheheʻe ʻana, ua centrifuged ka supernatant ma 2 ℃ ma 5000r / min no 40min, a laila kānana ʻia ma lalo o ke kaomi hoʻohaʻahaʻa (pulp filter a i ʻole 0.22μm microporous kānana membrane) no ka loaʻa ʻana o ka wehewehe ʻana o ka polypeptide ikaika. Thymus homogenate [extraction ma lalo o 10 ℃] → [-20 ℃, 48h] hau hau [80 ℃, 5min] → [5000r / min, 40min centrifuge] Active peptide extract ultrafiltration, hoʻomaʻemaʻe, hoʻopili, lyophilization ʻO ka extract i wehewehe ʻia o ka peptide ikaika. ʻO ka membrane ultrafiltration (hiki ke hoʻopaʻa i ka nui molekala pili ma lalo o 10,000) no ka loaʻa ʻana o ka hopena hoʻomaʻemaʻe. E kau i loko o ka friji ma -20 ℃. Ma hope o ka hala ʻana o ka hoʻāʻo, ua hoʻohui ʻia ka 3% mannitol (excipient), sterilized a kānana ʻia, hoʻopili ʻia, maloʻo maloʻo, a loaʻa iā thymosin no ka injection. Hoʻopili polypeptide ikaika [membrane ultrafiltration] → [Mr<10000] hoʻoheheʻe hoʻomaʻemaʻe [hoʻomaloʻo maloʻo] → [3% mannitol] thymosin no ka injection (E hoʻomaopopo: Pono e hoʻokō ʻia ke kaʻina hana holoʻokoʻa a me nā mea hana e like me ke ʻano hana aseptic.)

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