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Xov xwm

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  • Thymalin CAS 63958-90-7 whatsapp: +86-19031013676

Aug. Peb 08, 2023 15:20 Rov qab mus rau npe

Thymalin CAS 63958-90-7 whatsapp: +86-19031013676



Thymalin CAS 63958-90-7

Nws yog tsim rau thawj thiab theem nrab tiv thaiv kab mob tsis muaj zog, kab mob tshwm sim los ntawm kev tiv thaiv kab mob, kev kho mob ntawm cov qog, aplastic anemia, kab mob siab thiab mob ntev, thiab tseem tuaj yeem siv rau lupus erythematosus, rheumatoid mob caj dab, ua xua mob hawb pob, thiab lwm yam.

thymic yam xwm txheej kub kub taw tes 1658.9 + / - 65.0 ° C (Predicted) 1.417 + 0.06 g / cm3 ceev (Predicted) cia tej yam kev mob - 20 ° C solubility dChemicalbookeionizedwater: soluble acidity coefficient (pKa) 3.0 8 ± 0.10 (Predicted) Lyophilizedpowder Xim dawb

Serum thymus yog ib qho tseem ceeb los txhawb kev sib txawv ntawm lymphocytes thiab txhim kho nws txoj haujlwm. Nws tuaj yeem txhawb kev ua haujlwm ntawm lub cev tiv thaiv kab mob, tswj kev tiv thaiv kab mob thiab txhim kho kev tiv thaiv kab mob tsis muaj zog. Cov khoom siv tshuaj muaj peev xwm tswj hwm lub cev tiv thaiv kab mob ua haujlwm, nrog kev tiv thaiv kev laus, tshuaj tiv thaiv kab mob. Nws yog qhov ruaj khov rau cov cua sov, kev ua haujlwm lom neeg tsis txo qis ntawm 80 ℃, thiab cov khoom siv roj ntsha ploj tom qab raug hydrolyzed rau hauv cov amino acids. Cov calf thymus tau siv los ua cov khoom siv raw, roj, fascia thiab lwm cov ntaub so ntswg uas tsis yog thymus raug tshem tawm, tso rau hauv tub yees ntawm -20 ℃, ntxuav nrog dej distilled, thiab hauv av hauv cov nqaij grinder. Raws li qhov sib piv ntawm 1: 1, lub crushed thymus yog muab rho tawm nrog dej txias rau kev txhaj tshuaj (Suav dej yog muab rho tawm nrog tsawg permeability thiab txias melting), uas yuav ua rau lub active peptide siab soluble nyob rau hauv dej thiab txhim kho cov yield. Raws li cov ntawv tshaj tawm txawv teb chaws, nws tuaj yeem muab rho tawm nrog cov ntsev ib txwm) sib tov, muab tso rau hauv 10000r / min high-ceev cov ntaub so ntswg masher, thiab mashed rau 1min ua kom homogenize. Calf thymus [hauv av] → crushed thymus [cov dej txias rau kev txhaj tshuaj] → [10000r / min, 1min] Thymus homogenate ib feem ntawm thermal denaturation, centrifugation, pom Cov thymus homogenate tau tsau thiab muab rho tawm hauv qab 10 ℃, thiab tom qab ntawd khov ntawm -2chemical book0 ℃ rau 48h. Tom qab yaj, do hauv dej da dej thiab cua sov rau 80 ℃, khaws cia rau 5 feeb, txias sai sai, refrigerate ntawm -20 ℃ rau 2-3d. Tom qab melting, lub supernatant yog centrifuged ntawm 2 ℃ ntawm 5000r / min rau 40min, thiab ces lim nyob rau hauv txo siab (filter pulp los yog 0.22μm microporous lim membrane) kom tau clarified extract ntawm active polypeptide. Thymus homogenate [extraction hauv qab 10 ℃] → [-20 ℃, 48h] khov kua [80 ℃, 5min] → [5000r / min, 40min centrifuge] Active peptide extract ultrafiltration, purification, ntim, lyophilization Cov ntsiab lus nthuav tawm ntawm active peptide yog ultrafiltration membrane (uas tuaj yeem khaws cov txheeb ze molecular pawg tsawg dua 10,000) kom tau txais cov tshuaj ua kom zoo. Txias ntawm -20 ℃. Tom qab dhau qhov kev xeem, 3% mannitol (excipient) tau ntxiv, sterilized thiab lim, ntim, khov-qhuav, thiab thymosin rau txhaj tshuaj. Active polypeptide extract [ultrafiltration membrane] → [Mr<10000] refined tov [khov ziab] → [3% mannitol] thymosin rau txhaj tshuaj (Ceeb toom: tag nrho cov txheej txheem ua haujlwm thiab cov cuab yeej siv yuav tsum tau ua raws li txoj kev ua haujlwm aseptic.)

Qhia
Tom ntej:

Xov xwm tshiab
Asset 3

Xav tau kev pab?
Tso peb cov lus uas siv daim ntawv hauv qab no.

Yog tias koj txaus siab rau peb cov khoom, koj tuaj yeem xaiv tawm koj cov ntaub ntawv ntawm no, thiab peb yuav tiv tauj koj sai sai.


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