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  • Thymalin cas 63958-90-7 whatsapp: + 86-19031013676

Kanama. 08, 2023 15:20 Subira kurutonde

Thymalin cas 63958-90-7 whatsapp: + 86-19031013676



Thymalin cas 63958-90-7

Irakwiriye indwara zambere zo kubura ubudahangarwa bw'umubiri, indwara ziterwa no kudakora neza kw'umubiri, kuvura ibibyimba, anemia aplastique, hepatite ikaze kandi idakira, kandi irashobora no gukoreshwa kuri lupus erythematosus, rubagimpande ya rubagimpande, asima ya allergique, nibindi.

Serum thymic factor kamere iteka ingingo 1658.9 + / - 65.0 ° C (Biteganijwe) 1.417 + 0.06 g / cm3 ubwinshi bwububiko (Biteganijwe) - 20 ° C solubility dChemicalbookeionized water: coefficente acide (pKa) 3.0 8 ± 0.10 (Byahanuwe) Lyophilizedpowder Ibara ryera

Serum thymus ni ikintu cyingenzi cyo guteza imbere lymphocyte no kuzamura imikorere yayo. Irashobora gukangura ibikorwa byumubiri, igenga imikorere yumubiri kandi ikongerera ubudahangarwa bw'umubiri udasanzwe. Ibicuruzwa bivura imiti bishobora kugenzura imikorere yumubiri wa selile, hamwe no kurwanya gusaza, ingaruka za virusi. Birasa nkaho bihamye gushyuha, ibikorwa byibinyabuzima ntibigabanuka kuri 80 and, kandi ibikorwa byibinyabuzima birashira nyuma yo gushyirwamo aside aside amine. Inyana ya thymus yakoreshwaga nkibikoresho fatizo, ibinure, fassiya nizindi nyama zitari thymus zavanyweho, zikonjeshwa kuri -20 ℃, zogejwe namazi meza, hamwe nubutaka mu gusya inyama zanduye. Ukurikije igipimo rusange cya 1: 1, thimus yajanjaguwe ikurwamo amazi akonje kugirango itere inshinge (amazi yubushinwa akuramo amazi make kandi ashonga bikonje), bishobora gutuma peptide ikora neza gushonga mumazi kandi bikongera umusaruro. Nk’uko raporo z’amahanga zibitangaza, irashobora kandi gukurwamo na saline isanzwe) ivanze, igashyirwa muri 10000r / min yihuta yihuta, hanyuma igahundagurika kuri 1min kugirango ikore homogenize. Inyana ya thymus [hasi] → yajanjaguye thymus [amazi akonje yo gutera inshinge] → ℃ kuri 48h. Nyuma yo gushonga, koga mu bwogero bwamazi hanyuma ushushe kugeza kuri 80 ℃, gumana 5min, ukonje vuba, ukonjesha kuri -20 ℃ kuri 2-3d. Nyuma yo gushonga, ndengakamere yashyizwe kuri 2 ℃ kuri 5000r / min kuri 40min, hanyuma iyungurura munsi yumuvuduko ukabije (filter pulp cyangwa 0.22μm microporous filter membrane) kugirango ibone ibisobanuro bisobanutse bya polypeptide ikora. Thymus homogenate [gukuramo munsi ya 10 ℃] → [-20 ℃, 48h] igisubizo cyo gukonjesha [80 ℃, 5min] → ultrafiltration membrane (ishobora kugumana misile igereranije iri munsi ya 10,000) kugirango ibone igisubizo cyiza. Firigo kuri -20 ℃. Nyuma yo gutsinda ikizamini, hongewemo 3% mannitol (excipient), ihinduranya kandi irayungurura, ipakira, gukonjesha, na thymosine yo gutera inshinge. Igikoresho gikora polypeptide [ultrafiltration membrane] → [Mr <10000] igisubizo cyiza [gukonjesha gukonjesha] → [3% mannitol] thymosine yo gutera inshinge (Icyitonderwa: Igikorwa cyose nibikoresho bigomba gukorwa hakurikijwe uburyo bwo gukora aseptic.)

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